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MEF cell culture Control, Bmal1 / and Cry1 / Cry2 / MEFs were cultured in DMEM (Sigma-Aldrich) supplemented with 15% FCS (Atlanta Biological) and 1% penicillin-streptomycin at 37 C with 5% CO 2

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The conventional medicine response includes specialist referrals, symptom management, and normal lab results