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The peptide chelates divalent copper with high affinity, and the bound complex has been the subject of work on wound healing, hair follicle stimulation, anti-inflammatory effects in the skin, and a broad set of downstream gene expression changes related to collagen synthesis and extracellular matrix remodeling
& Velloso, L.A
L.MasonJ
Negroni A, Colantoni E, Cucchiara S, Stronati L
In this context, the concept of biased agonism 37 has emerged, in which ligands can selectively engage in different intracellular pathways, potentially allowing specific cellular responses
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