Understanding GLP-1 medications GLP-1 (glucagon-like peptide-1) receptor agonists, like semaglutide (the active ingredient in Ozempic and Wegovy), act like the GLP-1 hormone thats naturally made in your body
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doi: 10.1001/jamanetworkopen.2024.57349
It is also suitable for those with a BMI of 27 or higher who have weight-related health issues
Other medications commonly prescribed alongside GLP-1 therapy may contribute to erectile difficulties: Antihypertensives : Beta-blockers and thiazide diuretics are recognised causes of ED Antidepressants : Selective serotonin reuptake inhibitors (SSRIs) frequently impair sexual function 5-alpha-reductase inhibitors : Finasteride and dutasteride for prostate conditions can affect sexual function Antipsychotics : Can impact sexual function through various mechanisms Opioids : May reduce testosterone levels and affect sexual desire and function Spironolactone : Can cause hormonal effects that impact erectile function The relationship between statins and erectile function is complex, with mixed evidence
The SURPASS clinical trial program that included more than 10,000 patients in five pivotal trials indicated that tirzepatide provided a reduction in HbA1c (maximum of 2.4) (versus 1.5-1.8) and weight loss (maximum of 22.5) of baseline body weight at the highest dose of 15mg