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10.1186/1742-2094-9-5 J

Side effects such as mild nausea, constipation, or reduced appetite for previously enjoyed foods are common and usually subside by week 23 as your body adjusts

Mi H, Muruganujan A, Casagrande JT, Thomas PD

& Singh, N

(2002) Enzymatic oxidation products of spermine induce greater cytotoxic effects on human multidrug-resistant colon carcinoma cells (LoVo) than on their wild-type counterparts Int J Cancer