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Finally, participants were filtered on relatedness such that no two people shared more than 700 cM identity by descent 37 , which corresponds approximately to the minimal expected sharing between first cousins in an outbred population, resulting in a final GWAS sample size of 15,237

Upstream of any protocol decision, the PlexusDx Precision Peptide Genetic Test analyzes 14 pathways, 49 peptides, 150+ genetic insights, including variants in FTO, GLP1R, and MC4R that shape baseline GLP-1, appetite-regulation, and energy-balance biology

Boosts Vitality: Fill up essential vitamins and minerals, helping the body feel refreshed and reducing fatigue

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The first tier requires a BMI of 35 or higher at the time of GLP-1 therapy initiation