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Figure 4 Follicular helper T-cells (Tfh) exacerbate AS via major histocompatibility complex II (MHCII)-dependent B-cell differentiation into IgG-secreting plasma cells (63, 64), while cTfh1/cTfh2/cTfh17 subpopulations interact with neutrophils to amplify vascular inflammation (65)

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Shares of Eli Lilly and Novo Nordisk declined on the day of the announcement, as Amazons integrated model raised questions about the direct-to-consumer strategies both companies have built, according to Invezz

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