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Off-label use means the medication is being used in a manner not specifically approved by the FDA.

PMID: 42070571

The relationship between intestinal health and skin conditions is one of the most well-documented connections in dermatology, even if it remains underappreciated in conventional treatment approaches

This accumulation further poisons mitochondrial enzymes and exacerbates immune dysregulation

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Emerging evidence also implicates the gastrointestinal tract as a potential target of steroid toxicity