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GLP-1 is classified as an incretin hormone
Altered Glucagon and GLP-1 responses to oral glucose in children and adolescents with obesity and insulin resistance
Scientific research published in Diabetes Care confirms that GLP-1 therapies directly delay gastric emptying and reduce the rate at which food moves through the intestines, contributing to digestive symptoms
Approximately 15-25% of patients experience minimal weight loss despite therapeutic doses, driven by genetics, baseline metabolism, adherence patterns, and individual receptor sensitivity
En cuanto al peso, hubo disminucin significativa en ambos grupos a las 24 y 52 semanas, pero el grupo sin AGLP1 perdi ms peso, 2.3 vs 3.9 kg a las 24 semanas y 2.4 vs 4.8 kg a las 52 semanas
Understanding potential overlapping side effects, monitoring requirements, and UK regulatory guidance is essential
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