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In addition to the consensus on the prominent role of cystine starvation in blocking GSH synthesis, the present two studies demonstrated two previously under-appreciated metabolic effects that contribute to the ferroptosis-susceptible state in cancer cells under cystine deprivation conditions: loss of GPX4 protein translation and accumulation of oxidative stress-inducing intracellular glutamate (Fig
The severity of preeclampsia seems to be related to the severity of glutathione deficiency
For children aged 114 years, the AIs increase with age from 1.5 to 3.5 g/day
Update 21 , 427454 (2015)
10.1016/0006-291x(86)90387-6 546 SoloukiT.GilligK
Insulin acts to retain sodium in the body and that results in an increase in blood pressure
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