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Development of a novel amylin analog for potential obesity research

Hedegaard, M

CJC-1295 with DAC modification may show slightly improved stability due to its larger molecular structure

Peptide degradation pathways Tirzepatide is a 39-amino-acid peptide with specific structural modifications that make it effective, including alpha-aminoisobutyric acid (Aib) substitutions at positions 2 and 13 (which protect against DPP-4 enzyme degradation in the body) and a C20 fatty diacid chain at position 20 (which enables albumin binding for a longer half-life)

Bassi V, et al

It has been explored for its role in supporting ligament, tendon, muscle, and gastrointestinal integrity