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ROS-mediated activation and mitochondrial translocation of CaMKII contributes to Drp1-dependent mitochondrial fission and apoptosis in triple-negative breast cancer cells by isorhamnetin and chloroquine

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Do not increase dose prior to 3 weeks

Multi-receptor agonism can, in principle, achieve greater effects by recruiting complementary mechanisms, producing effects no single engagement can, and offsetting side effects at one receptor through actions at another

Patient with high CK-MB, troponin, no chest pain

[1] While this is not a formal contraindication in the UK (unlike in the US), your prescriber may exercise caution based on your individual risk factors and medical history