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Courts often focus on what was known, what was foreseeable, and whether continued caution would have been reasonable

They differ in formulation and are prescribed only pursuant to an individualized medical determination by a licensed healthcare provider

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A rapid dissociation rate is also required to allow ligands to leave the receptor timeously after activation, to avoid internalization and ultimately maintain the quantity of the incretin receptors in the body

Chen P, Yang F, Wang W, Li X, Liu D, Zhang Y, Yin G, Lv F, Guo Z, Mehta JL