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doi:10.1016/j.jdiacomp.2017.06.010 Raygan F, Taghizadeh M, Mirhosseini N, et al

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Generally, biologic activity of ATRA such as gene expression or inhibition through direct DNA interaction is being exerted by binding to nuclear retinoid receptors (ligand-activated transcription factors) like (all- trans ) retinoic acid receptors (RARs) or retinoid X receptors (RXRs) which together build a heterodimer [83, 96,97,98,99]

In addition, AC could ameliorate hepatic lipid peroxidation and successfully inibit hepatic histopathological damage induced by STZNA in those diabetic rats

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Improve digestive function Suggested Use: Take one capsule twice per day, or as recommended by your healthcare provider