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Clinical trials indicate it may take around 16 weeks to lose 5% of body weight on tirzepatide 5mg and 24 weeks on semaglutide 1mg, alongside diet and exercise
ROS accumulation mediated by FGF23 worsens Ca 2+ influx and PS exposure, thereby promoting faster erythrocyte removal (Mehta et al., 2017)

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Genazzani, Alessandro D., et al