Medicine & Science in Sports & Exercise , 44(4), 770778
Will be definitely purchasing more* Was this helpful
Some care may be required in selecting which populations to target with which interventions metformin, for example, might be a good choice to test for people with established sarcopenia but could worsen muscle function in healthy older people without sarcopenia
However, they do confirm that the lean-mass loss seen on GLP-1s is a feature of the energy deficit, not the drug, and it responds to interventions that signal muscle preservation
This limitation applies particularly to pharmacological agents that modify AMPK, mTOR, redox signaling, or inflammatory cascades in parallel with autophagy-related processes
If experiencing erectile dysfunction while taking semaglutide, it is recomended to speak with a doctor to determine if its related to the medication or another cause