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Moreover, oxidative stress upregulates adhesion molecules like intercellular adhesion molecule-1 (ICAM-1) and vascular cell adhesion molecule-1 (VCAM-1) on orbital fibroblasts and endothelial cells, facilitating immune cell recruitment and adhesion to inflamed orbital tissue (88, 89)

Platelets have essential roles in a wide range of biological processes, including but not limited to hemostasis, thrombosis, inflammation, infection, immunobiology, cancer metastasis, wound repair, and angiogenesis (159)

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