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Even in low-risk Group 1, SGLT2is use was common among older patients with moderate eGFR decline, reflecting early targeting of subclinical risk

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Other outcomes were pharmacodynamic parameters including the international normalized ratio (INR) of the prothrombin time (warfarin studies), lipid levels (statin studies) and gonadotropins or progesterone levels (combined oral contraceptive [COC] studies)

Castorena-Gonzalez, Joseph Rutkowski and Evan Rosen for their contribution to the peer review of this work