For broader context on the best peptides for weight loss , semaglutide at 2.4 mg remains one of the most effective single agents available, with results rivaling some combination approaches
And unlike semaglutide, the weight loss trajectory with retatrutide did not appear to plateau at 48 weeks
Here's what's actually happening and what to do about it
The drugs, semaglutide (Ozempic and Wegovy) and tirzepatide (Mounjaro and Zepbound) are very expensive, with list prices of over $15,000 annually, and net employer prices of about $9,000 annually after rebates and discounts
Additionally, trial participants who discontinue due to side effects or lack of efficacy are often excluded from certain analyses, which can inflate the apparent average effect
Maybe I want more of that, but its okay