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The term purity is most accurate when applied to raw peptide materials, isolated compounds, or lyophilized peptide powders where a single active compound is measured against potential impurities

Potential concerns include effects on angiogenesis that theoretically could influence tumor development or progression, though preclinical studies show context-dependent effects that inhibit pathological angiogenesis in some tumor models

The evidence base, such as it is, differs meaningfully across clinical targets, and it is worth examining each major application area on its own terms

2 The main sources of cellular ROS are mitochondria and nicotinamide adenine dinucleotide phosphate (NADPH) oxidases, and peroxisomes containing xanthine oxidase and the inducible form of nitric oxide synthase, which produce superoxide anion and nitric oxide, respectively

The most immediate issue is gastrointestinal discomfort