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Next Retatrutide, Cagrilintide, are going to be the upcoming molecules in the market.....

Wadden TA et al

Effects of the once-weekly glucagon-like peptide-1 receptor agonist dulaglutide on ambulatory blood pressure and heart rate in patients with type 2 diabetes mellitus

GLP-1 receptor activation directly engages this same pathway

the small-molecule world will look to do the same, but likely as fixed-dose combinations of two or three orals rather than as single multi-functional peptides until true dual and triple small-molecule agonists can be found