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3.3 Glutaminase inhibition affects mitochondrial respiration and energy metabolism in CLL cell lines but can be successfully compensated for by glycolysis In the HG-3 and MEC-1 cell lines, CB-839 treatment caused dose-dependent decreases in the OCR, including the basal OCR, maximal respiration rate, and spare respiratory capacity

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Side Effects: While rare, side effects from the lipotropic components can occur, including gastrointestinal discomfort, fatigue, and allergic reactions

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