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The above dosages and indications are general guidelines and may vary based on individual patient needs and clinical judgment

The Danish drugmaker plans to launch Extensior, a lower-cost authorised version of Ozempic, in South Africa on 27 July through a partnership with Swiss healthcare company Acino

Unlike some medications that accumulate in kidney tissue, tirzepatide is primarily hepatically metabolized, making it suitable for patients with mild-to-moderate CKD stages

Studies also suggest these drugs can also affect the brains hypothalamus-pituitary-gonadal axis, which regulates reproductive hormones and menstrual cycles

The standard approach assumes these peptides operate in separate metabolic lanes