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Eight weeks of aerobic exercise significantly activated the System Xc /GPx4 signaling pathway in the prefrontal cortex of APPswe/PS1dE9 transgenic AD mice, up-regulated FTL and BACE1 expression, significantly downregulated 4-HNE levels, inhibited oxidative stress, lipid peroxidation, and ferroptosis, reduced A positivity, alleviated neuronal morphological abnormalities, and improved learning and memory functions in AD mice (Li et al., 2024a)
Lancet Diabetes Endocrinol 2021;9:653-62.ArticlePubMed 75
Vegetarian and vegan diet in fibromyalgia: a systematic review
2012 Mar;153(3):1538-47
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In addition, we showed that GSH depletion induces autophagy and SIPS, with autophagy being a negative regulator of SIPS
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