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If a patient receives a dosage significantly higher than advised, serious side effects like renal failure or blood poisoning may manifest

16(48): 60876097 Alexander M Mathes, et al Influence of the Circadian System on Disease Severity Litinski M, Scheer FA, Shea SA Sleep Med Clin 2009 Jun 1

*Correspondence: Omar Dzaye [email protected] These authors share first authorship This article was submitted to Cardiovascular Therapeutics, a section of the journal Frontiers in Cardiovascular Medicine Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

A change may be possible for some patients, but it should not be done without medical guidance

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