Its always followed by further instruction
SYMLIN has not been studied in patients with end-stage renal disease [see Clinical Pharmacology (12.3)]
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Smedler E, Louhivuori L, Romanov RA, Masini D, Dehnisch Ellstrom I, Wang C, et al
On the other hand, the pill form requires daily doses, so patients may need more frequent refills
In a Phase 2 randomised controlled trial published in the New England Journal of Medicine in 2023 (Jastreboff et al., NEJM 2023), adults with obesity (without type 2 diabetes) who received the highest dose of retatrutide (12 mg weekly) achieved a mean body weight reduction of approximately 24% over 48 weeks