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Sixth, regarding statistical limitations, the modest sample size and exploratory nature of the analyses limited the power for extensive multivariable adjustment and detection of rare safety events

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Note: results were achieved under controlled trial conditions with behavioural and dietary support

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Pathogenic genetic variants in one of three genes encoding for amyloid precursor protein ( APP ), presenilin-1 or presenilin-2 lead to a form of the disease known as early-onset familial AD, which accounts for 510% of AD cases 1