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10.1016/S0015-0282(16)56520-0 98

The terms of the settlement are confidential and it remains unclear whether generic entry will happen once the main compound patent expires or later due the follow-on patents

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At the oxidative stress level, excessive generation of ROS and antioxidant system imbalance have been observed to not only directly damage intestinal mucosal cells but also to influence immune cell differentiation and barrier repair through modulation of signaling pathways, thereby creating a vicious cycle of inflammatory progression [12, 29]

Although research is limited, some studies suggest that it boosts short-term weight loss by altering the composition of your gut microbiome, reducing inflammation, and improving insulin sensitivity