These medications target receptors in the brain specifically in the hypothalamus and hindbrain to curb appetite and reduce constant thoughts about food, often referred to as "food noise." "Lots of people describe it as decreasing food noise, which means how much you think about food and how much you crave different foods." Evan Nadler, MD, MBA, Adjunct Associate Professor, George Washington University Myth 5: GLP-1 Medications Are Only for Type 2 Diabetes Although GLP-1 medications were initially created to manage diabetes, they now have FDA approval for chronic weight management in people without diabetes
doi: 10.1002/cphy.c210002 29 CalvoSSCEganJM
This change in appearance after weight loss with GLP-1 agonist medications is often referred to as GLP-1 face
The most immediate change I noticed was a dramatic reduction in my appetite and food noise
Again, some level of consideration will have to be made for initial starting BMI, but just like the obese patients, a treat-to-target dose that considers weight + A1c goals should be the aim going forward
Scala projected even higher sales for the GLP-1 drugs than FactSet$3.895 billion for Mounjaro, an even $1.5 billion for Zepbound