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Recent reports demonstrated that GSH depletion triggers ferroptosis in some cell types 18

Thyroid Tumors: Animal studies suggest a potential risk for certain thyroid tumors, though the relevance to humans is still under investigation

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via NADPH oxidase 2 (NOX2)-dependent production of superoxide and hydrogen peroxide) is also necessary for PI3K/AKT-dependent NSC self-renewal (Le Belle et al., 2011)

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doi:10.1089/cap.2006.16.541CrossRefGoogle ScholarPubMed Fido, A, Al-Saad, S