Although, most participants lost weight, there was heterogenicity, that has been well-documented in obesity studies [66] and those with higher BMI above 35 experienced greater mean percentage weight loss [64]
These tests included a hot water test (60C), cold water test (2C), walking track analysis, EMG-distal latency, and amplitude of CMAP
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Downstream metabolic improvements changes in cortisol, insulin sensitivity, or body composition require longer windows of 612 weeks, and depend substantially on whether DSIP is used as part of a broader supervised metabolic protocol rather than in isolation
