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Diane-35 and Yaz contain the type of progestin that has the least androgenic activity among the other progestins
doi:10.1007/s001250051335 119
HDACs play a critical role in transcription regulation by removing the acetyl groups of lysines on histone tails
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Also, after treatment of this cell line with the Akt inhibitor, MK2206 or the mTOR inhibitor (rapamycin) reduced the expression of Vimentin and SLUG (as EMT biomarkers)
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