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Recent evidence indicates that the kind and amount of protein are essential for muscle hypertrophy and athletic performance, with individual differences in protein consumption and amino acid absorption-metabolism associated with both protein quantity and quality, as well as genetic variances between persons (545)

Cross-disease comparisons suggest that these modules recur across different organ niches, but their net effects are markedly context-dependent and are jointly regulated by disease stage (acute inflammation versus chronic tissue remodeling), tissue compartment (peripheral blood versus lesional tissue), as well as the spectrum of stimuli and therapeutic exposure, thereby leading to inconsistent directional outcomes of the same pathway across different models and time windows

The authors additionally acknowledge: (a) Christopher Jadelis (at UNC Chapel Hill) for his assistance on the experimental setup

Stay Hydrated: Water intake supports kidney clearance

Dalton, TP (2002)