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Like the injectable version, it works by mimicking a naturally occurring hormone called GLP-1, helping to regulate appetite, reduce hunger and increase feelings of fullness

Nature 379: 69-72, 1996

These studies look at how it affects people over time, showing possible risks and benefits for managing type 2 diabetes and supporting weight loss

The full picture of how retatrutide works in various situations will become clearer

The percentages above are from separate trials with different populations and durations, so direct comparison requires caution

Understanding this mechanism is critical for understanding why specific retatrutide doses produce the results they do