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How IGF-1 LR3 Works IGF-1 LR3 is an analog of naturally occurring IGF-1, a hormone that plays a key role in growth, cellular repair, and metabolism

PubMed, doi:10.1158/1055-9965.EPI-08-0917

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Specifically, bloodletting puncture can suppress the expression of MAPK, ERK, p38, and their downstream molecules, MMP9 and AQP4, leading to enhanced neurological function, reduced brain edema, stabilization of the bloodbrain barrier, and decreased apoptosis