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a , Functional networks of interest are delineated on cortical surfaces: the somato-cognitive action network (SCAN, purple) and the effector motor regions (blue) including the foot, hand, and mouth networks

Several papers describe upregulation of the vascular endothelial growth factor receptor 2 ( VEGFR2 ) pathway and downstream nitric oxide signalling the so-called VEGFR2-Akt-eNOS axis which researchers hypothesise underlies its reported influence on wound healing and blood-flow restoration at an injury site