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The original nomogram line separating possible toxicity from unlikely toxicity was based on a 4-hour acetaminophen concentration of 200 micrograms/mL (1300 micromoles/L), but was subsequently modified by moving the line to a 4-hour acetaminophen concentration of 150 micrograms/mL (1000 micromoles/L) to increase the safety margin for treatment decisions
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10.2174/138161210790945977 117 SikiricP.SeiwerthS.GrabarevicZ.BalenI.AralicaG.GjurasinM.et al (2001)
Maintenance sessions are advised to sustain the effects
SUSTAIN 5: As an add-on to basal insulin vs placebo 1,10 Study design: 30-week, randomized, double-blind, placebo-controlled, parallel-group, multinational, multicenter trial to compare the efficacy and safety of Ozempic injection in combination with basal insulin vs volume-matched placebo in combination with basal insulin
