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Results develop progressively and may last up to two years or longer in some patients

In this study, twice-daily exenatide treatment was associated with a lower risk of CVD events including MI, ischemic stroke, or coronary revascularization procedure (hazard ratio [HR], 0.81

In conclusion, we found that l-valine is a powerful stimulator of GLP-1 secretion both in rats and mice (ex vivo and in vivo), and we suggest a mechanism for l-valine stimulated GLP-1 release involving intracellular metabolism of the amino acid, leading to the closure of K ATP -channels, membrane depolarization and activation of V-gated Ca 2+ -channels (Fig

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Panayotou, H

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