Preclinical studies have shown that GIP may reduce body weight by reducing food intake and increasing energy consumption, and in combination with GLP-1 receptor agonists, may have a greater effect on patients' blood glucose and body weight
It is important to approach this discussion with realistic expectations, given that retatrutide does not currently hold a UK marketing authorisation and is therefore not available as a standard prescription medicine
Limited access to GLP-1s in low-income and high-obesity regions threatens to widen existing health inequities, particularly in rates of diabetes, cardiovascular disease, and mobility-related conditions
It is expected to become a new target for the treatment of metabolic disorders
It is also recommended for persons with type 2 diabetes to lower the risk of serious cardiovascular events
Similar exposure to semaglutide is achieved regardless of injection site