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With off-label use, doctors prescribe a drug for a use other than an FDA-approved use

[DOI] [PubMed] [Google Scholar] Pandya A, Berneburg M, Ortonne JP, Picardo M

The SELECT trial, which supports the expanded indication, enrolled patients 45 years of age and older with pre-existing cardiovascular disease and a body-mass index of 27 or greater without diabetes

Now, if people with long COVID and severe PEM are largely stuck in their homes or beds and excluded from trials, is the long COVID research as it stands representative of the full population of people with long COVID