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doi:10.1016/j.ijcard.2022.05.056 Tonhajzerova I, Sekaninova N, Bona Olexova L, Visnovcova Z

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Retatrutide's 24.2% at 48 weeks in a smaller phase 2 trial suggests a numerically greater weight loss signal, attributed in part to the added GCGR-mediated energy expenditure increase, but no head-to-head RCT exists

On paper, it appears that Zepbound may be the superior weight loss drug offered at a lower price than Wegovy, acting as a dual agonist mimicking 2 gut hormones instead of just GLP-1

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