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And what are these new weight loss drugs anyway

A 32-year-old non-diabetic woman with obesity and NAFLD saw minimal progress with semaglutide

5 One large observational study showed 31% of people switched to a different anti-obesity or GLP-1 receptor agonist or restarted tirzepatide after stopping it

I would not recommend microdosing GLP-1s for individuals with significant amounts of weight to lose or known metabolic dysregulation. The bottom line is that there are still questions regarding the effectiveness and safety of microdosing GLP-1 medications, and this type of regimen is not for everyone

my buddy felt sick right away but not me

They stimulate insulin secretion from pancreatic beta cells in a glucose-dependent manner, meaning insulin is released only when blood glucose levels are elevated