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doi: 10.1038/s41598-023-39444-4 7 NiYZhengLNanSKeLFuZJinJ
Endogenous glutathione synthesis from dietary cysteine, glutamate, and glycine is typically sufficient unless you're in a state of severe oxidative stress or hepatic compromise
A healthy balance of reduced and oxidized forms of L-glutathione supports the bodys ability to detoxify chemicals such as those found in environmental pollutants, smoke and exhaust, heavy metals, and metabolites from various types of drugs
These changes can impact both mucosal integrity and immune tolerance, leading to greater gut permeability, which has been reported to precede clinical onset of T1D (131)
Johansson AS, Ridderstrm M, Mannervik B