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Many users report swelling and edema (fluid build-up) in the arms, legs, and face

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Neural Regen Res 13(11):18791882 Branca JJV, Fiorillo C, Carrino D, Paternostro F, Taddei N, Gulisano M et al (2020) Cadmium-induced oxidative stress: focus on the central nervous system

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Consequently, fluid transparency was better in the coffee enema with PEG group than that in the PEG-only group in the mid and distal segments and the terminal ileum (p = 0.04, p = 0.007, and p = 0.002, respectively, Figure 1)