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10.1590/1414-431x20198132 138 ZhangD.Al-HendyM.Richard-DavisG.Montgomery-RiceV.RajaratnamV.Al-HendyA

Its primary researched functions include promoting cell migration (getting healing cells to the injury), down-regulating inflammation, and encouraging the growth of new blood vessels

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Vomiting, anorexia, headache, irritability, tremors, and palpitations, can be overdose syndromes (33-34)

Mitochondria affect ferroptosis at the level of the cytosolic iron pool regulation by fine-tuning the iron influx from the cytosol into mitochondria, at the level of electron transport chain by adjusting mitROS generation and oxidative phosphorylation via AMPK activation in the energy-deficient state, and at the level of tricarboxylic acid (TCA) cycle affecting the content of NADPH and GSH [162, 166]

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