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Studies have shown that chronic hyperglycemic diets increase the risk of colon cancer, in part by regulating the insulin/IGF-1 signaling axis by activating the downstream PI3K/AKT/mTOR, Ras/MAPK signaling pathways, glucose transporter proteins (GLUT1) and key enzymes of glycolysis (LDHA and HK2), thereby affecting glucose uptake and aerobic glycolysis in cancer cells (65)

Ferroptosis Currently, the most comprehensive understanding of the role of lipid peroxidation in cell death is through ferroptosis (Fig

What Happens if GLP-1 Is Not Refrigerated

NF-kappaB: A key role in inflammatory diseases

Chorley, B

Results were normalized to the control group, and proliferation curves were plotted