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When stomach emptying slows significantly, the timing and amount of hormone absorption may shift, potentially affecting contraceptive efficacy

Those wishing to access it should do so only through legitimate, registered clinical trials

I will say there are a lot of anecdotal reports about initial insomnia and elevated heart rate (presumably lowered HRV) on the forums, and I did experience that when starting tirzepatide and when trying retatrutide, but the insomnia and heart rate issues seemed transient

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B.Pereira-SampaioM

So Kispeptin is obviously a key player in this whole pathway of steroid hormone release, the steroid hormones being testosterone and estrogen