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doi: 10.1007/BF02968584

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Recently, researchers found that HD showed antioxidant, antiinflammatory and proapoptotic activities by significantly prevented thioacetamide-activated Wnt3a/-catenin and Wnt5a pathways in thioacetamide-induced early HCC model in rats, which suggested that HD exhibited an antitumor and hepatoprotective effects against the development of HCC (Zaghloul et al., 2017)

10.3390/nu12061742 19 ItohK.ChibaT.TakahashiS.IshiiT.IgarashiK.KatohY.et al (1997)

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4.1 Co-regulation of mitochondrial biogenesis and mitophagy Mitochondrial-related pathways are intertwined, convergent, and differentiated (Palikaras et al., 2015)