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In the peripheral blood, Fe ions are in a bound form with transferrin, ferritin, lactoferrin, ceruloplasmin, which are Fe 2+ chelators and perform an antioxidant function

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XL413, a cell division cycle 7 kinase inhibitor enhanced the anti-fibrotic effect of pirfenidone on TGF-beta1-stimulated C3H10T1/2 cells via Smad2/4

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