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Notably, SHMT2 is a mitochondrial enzyme contributory to one-carbon metabolism by converting serine and tetrahydrofolate (THF) into glycine for GSH synthesis and a one-carbon unit, 5,10-methylenetetrahydrofolate (5,10-CH 2 -THF), for dTTP synthesis 35 , respectively

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(2021) [77], provide valuable insights into SFNs multifaceted role in suppressing GC cell growth and triggering apoptosis, thus highlighting its potential as a novel therapeutic agent for the treatment of gastric cancer

The total formulation contains 80mg of active compounds distributed across complementary mechanisms of action