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No Genetic Cure: Patients must remember that these therapies, however helpful, do not cure the genetic cause of EDS

Large randomized controlled trials in humans are absent, so clinical efficacy claims lack robust evidence

Long-term studies demonstrate sustained improvements in physical capacity and metabolic function following senescent cell clearance, suggesting FOXO4-DRI treatment can fundamentally alter aging trajectories

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Many men hate going to the Doctor to discuss some of their personal issues

Injectable use in humans represents off-label experimental application with limited long-term human safety data specifically for injectable formulations